Searchable abstracts of presentations at key conferences in endocrinology

ea0016oc2.3 | Thyroid | ECE2008

Global proteomic analysis in human thyroid proliferative/neoplastic primary culture lines

Bravo SB , Garcia-Rendueles MER , Ciordia S , Juarez S , Paradela A , Cameselle-Teijeiro J , Albar JP , Alvarez CV

Proteomics provides an avenue to understand the interaction between the functional pathways within a cell and its environmental milieu, independent of any changes at the RNA level. There are only a few studies in thyroid diseases using proteomics; variability in specimen content in fibrous versus follicular tissue plus the presence of other types of cells (blood, lymphatic) makes difficult to apply global proteomic to surgery pieces; commercial cell-lines of thyroid cancer wer...